Diet plays a central role in your dog’s overall health and well-being, and it stands to reason that you want to provide your dog the best possible source of nutrition in the dog food you choose. But some nutrients, like L-Carnitine, may be unfamiliar or completely foreign. Learn more about this vitamin-like compound and how it can help your dog maintain a healthy weight.
Carnitine, or L-carnitine, is a vitamin-like compound made in the body from amino acids. It's found naturally only in animal-based protein sources. It has been used to help with fat metabolism in other species, and recent scientific studies show that it can help reduce weight in overweight dogs.
This water-soluble substance attaches to fatty acids, transporting them into cellular mitochondria, the part of the cell that converts fat into a usable form of energy. There, they are broken down through oxidation and converted to energy for all tissues, including the heart, liver, and skeletal muscles. Through this process, carnitine helps reduce the storage of body fat and the amount of fat in the bloodstream.
In a study conducted by The IAMS™ Company, overweight dogs were fed similar diets. One group was given a diet supplemented with L-carnitine while another group received a diet without supplemental L-carnitine.
After seven weeks, the group that received the diet without supplemental L-carnitine lost 1.8% body weight compared to 6.4% body weight loss from the group that was fed the L-carnitine supplemented diet. Likewise, body fat was reduced in each group by 2.4% and 4.6%, respectively.1 The study found that L-carnitine promotes loss of body weight and body fat in overweight dogs.
IAMS™ ProActive Health™ Adult Healthy Weight is formulated with L-carnitine that helps turn fat into energy, providing a path to help keep him fit for life.
1 Sunvold GD, Tetrick MA, Davenport GM, Bouchard GF. 'Carnitine supplementation promotes weight loss and decreased adiposity in the canine.' Proceedings of the XXIII World Small Animal Veterinary Association. p. 746. October, 1998.

Antioxidants are nutrients found naturally in the body and in plants such as fruits and vegetables. Common antioxidants include vitamin A, vitamin C, vitamin E, and certain compounds called carotenoids (like lutein and beta-carotene).
As cells function normally in the body, they produce damaged molecules called free radicals. These free radicals are highly unstable and steal components from other cellular molecules, such as fat, protein, or DNA, thereby spreading the damage.
This damage continues in a chain reaction, and entire cells soon become damaged and die. This process is called peroxidation. Peroxidation is useful because it helps the body destroy cells that have outlived their usefulness and kills germs and parasites. However, peroxidation, when left unchecked, also destroys or damages healthy cells.
Antioxidants help prevent widespread cellular destruction by stabilizing free radicals. More important, antioxidants return to the surface of the cell to stabilize, rather than damage, other cellular components.
When there are not enough antioxidants to keep peroxidation in check, free radicals begin damaging healthy cells, which, in turn, can lead to problems. For example, free-radical damage to cells of the immune system can lead to an increased risk of infections.
Because antioxidants play a key role in minimizing damage to human cells, such as those that make up the immune system, research examined the benefits of certain antioxidants on the immune response of dogs. The results of these studies indicated that antioxidants are important in helping dogs maintain a healthy immune system.